How to Safely Monitor Small Animal Neurology Patients During MRI: Essential Anesthesia and Monitoring Tips

Author

Elizabeth Goudie

How to safely monitor your patient during MRI can feel overwhelming especially when faced with tricky cases. Elizabeth Goudie DVM, MS, DACVAA, discusses how – with some simple planning and the right  monitoring – we can help alleviate some of these anxieties when presented with an MRI patient, and work to improve patient care.

Why Careful Monitoring Matters During MRI

Small animal neurology patients undergoing MRI often present with conditions such as intervertebral disc disease, cervical spine disorders, or intracranial lesions. Even those with seemingly minor neurological issues may have comorbidities that increase anesthetic risk. Understanding how to safely monitor these patients during MRI is key to optimal outcomes.

MRI procedures limit hands-on monitoring, making anesthesia management challenging and sometimes overwhelming for even the most seasoned of anesthetists. With strategic planning, and MRI-compatible monitoring equipment, veterinary teams can reduce risk and improve patient outcomes.

Successful preparation is essential to safely monitoring your patient during an MRI and should include:

• Providing heat on the induction table
• Obtaining a baseline ECG and blood pressure
• Preoxygenate all patients for 3-5 minutes before intubation.
• Using a multiparameter monitor during the scan
• Maintaining normothermia at induction and during preparation will help prevent hypothermia in the MRI
• Closely monitoring the patient in the recovery period

Perhaps, most importantly, all abnormalities and concerns should be communicated between the dedicated team members. This includes a dedicated anesthetist, a dedicated imaging technician, and the case doctor. Rounds before the case, and discussion of any patient concerns during the imaging process, help alleviate any miscommunications that could negatively impact the patient’s outcome.

Pre-Anaesthetic Assessment for MRI Patients

When preparing for an anesthetic episode, treat the MRI patient as you would any patient undergoing surgery or other procedure. A thorough review of the patient’s history and recent bloodwork is essential. A good rule of thumb is within the month if no significant medical changes have occurred recently, and diagnostics. A perianesthetic checklist should also be incorporated.

• Physical examination: evaluate the patient’s cardiovascular, respiratory, and neurological systems to identify any underlying conditions that could affect anesthesia including any history of metallic implant/foreign body

• Diagnostic tests: perform pre-anesthetic blood work (e.g., CBC, biochemistry panel) to assess organ function and identify any abnormalities

• Risk stratification: classify the patient’s anesthetic risk (e.g., ASA status) to tailor the anesthesia protocol

Multiparameter Monitoring

It is important to monitor our small animal neurology patients at the same level as we monitor our other patients, particularly those patients with intracranial lesions. Anesthesia quickly disrupts homeostasis, and having a way to closely watch for disruptions, especially in higher ASA status patients, is vital because we are unable to place hands on our patients during the scan. Minimum recorded parameters should be:

• Every 5 minutes: Heart rate, respiratory rate, end-tidal carbon dioxide, and blood pressure

• Every 15 minutes: Pulse oximetry and temperature

While recording occurs every 5- 15 minutes, all monitoring should be applied to the patient and observable throughout the procedure.

ECG Monitoring

While the use of this modality is prone to artifacts, it’s use is still recommended:

• Obtain a baseline ECG before inducing to ensure no underlying arrhythmias
• Artifacts are due to magnetohydrodynamic (MHD) effects that alter the ECG signal as well as magnetic field gradient switching
• Between scans or during less disruptive scan sequences, it is a reliable modality

Bradyarrhythmias are not uncommon in small animal neurology patients undergoing MRI. They can occur due to several factors, including increased intracranial pressure, which affects autonomic regulation; breed predispositions such as in Dachshunds; the use of certain drugs like opioids and dexmedetomidine that depress heart rate; and hypothermia, which commonly develops during prolonged anesthesia and imaging procedures.

The use of MRI-specific leads, including MRI-specific adhesive ECG pads, should be adopted to prevent injury, damage to the MRI, or artefact.

Monitoring pulse oximetry (SpO₂)

Pulse oximetry offers a way to monitor heart rate when ECG or invasive blood pressure heart rate is unavailable. Artifacts do occur but less consistently than with ECG.

• The plethysmograph (pulse oximetry waveform) can also provide valuable information. Pulse pressure variation can show the need for fluid resuscitation.
• Changes to the waveform can indicate arrhythmias that may not be observable on ECG due to artifact
• Covering the probe insulates it from ambient light and can improve results
• When placing the pulse oximeter, consider other locations besides the tongue.
• For probes that wrap, shaving the ventrum of the tail and placing the probe around the tail prevent the tourniquet effect – or slipping – that is often observed when using the tongue.
• Ensure the probe used is MRI-safe to avoid artefacts

Monitoring Blood Pressure

When monitoring blood pressure in small animal neurology patients, some monitors are more reliable than others when it comes to oscillometric measurements:

Monitoring End-Tidal CO2

This modality is probably our most reliable when it comes to artifacts during the MRI scan.

• It is vitally important to monitor when there is risk of ICP elevations: End-tidal CO₂ should be maintained at 35-40 mmHg for patients with increased intracranial pressure

  • All other patients normocapnia (35-45 mmHg) or mild permissive hypercapnia (<55 mmHg)
• Many patients anesthetised for MRI are mechanically ventilated; capnography is used to help tailor the ventilator settings
  • If patient will spontaneously ventilate and the MRI scan is not negatively impacted, I prefer to allow the patient to spontaneously ventilate to maintain blood pressure/venous return and ensure spontaneous ventilation at the end of MRI so speeding the recovery process.

MRI-Compatible Equipment

When it comes to safely monitoring your small animal neurology patients during an MRI scan, it’s a good idea to research compatible equipment such as ventilators, monitors, fluid pumps and heating. This is by no means an exhaustive list, but some of those to consider are:

Ventilators

There are many MRI-safe ventilators available including (but not limited to):

• Hamilton Medical: a newer, MRI-compatible ventilator allowing for easier settings with multiple advanced ventilation mode settings

• Penlon-Nuffield: a pneumatically driven ventilator which may – initially – be harder to learn to use

• Hallowell: a simple volume cycled ventilator that many veterinary staff are comfortable with

Monitors

MRI-safe monitors include:

• Iradimed: A reliable monitor that remains in the room with the patient. A separate tablet is placed in the anteroom. Multiparameter including ability to add invasive blood pressure

• Digivet (Digicare) LifeWindow. A veterinary-specific monitor with MRI safe/compatible connections with the monitor located outside the MRI room. Cords are passed through waveguide

• SAII Model 1035 MR compatible: A veterinary-specific monitor providing a combination of in the room and outside, with the monitoring module outside the MRI room and parameters on a PC screen. ECG does NOT require shaving for pad

• Tesla M3: An MRI-safe monitor that remains in the MRI room with a remote MRI monitor. A multiparameter includes IBP and anesthetic gas monitoring

• Phillips: The Invivo is the older model of company’s MRI monitors. NIBP can be unreliable due to small patient size and often requires IBP in very small, vasoconstricted patients. Their new anesthesia monitor, Expression, is also worth considering.

Fluid Pumps

Fluids should be provided for these MRI patients. Partial intravenous anesthesia or total intravenous anesthesia can be administered either within the patient’s IV fluid bag or in a smaller bag, both using standard administration sets. Alternatively, MRI-safe syringe pumps or Faraday cages can be used to allow for small-volume CRIs.

While there are MRI-compatible IV fluid pumps (Iradimed and MedRad) many hospitals will have a standard pump outside the MRI room with extensions through the wall or outside of the 5-gauss line.

Heating

Many of the monitors listed here allow for surface or corporeal temperature monitoring. The maintenance of normal body temperature in MRI greatly improves the anesthetic episode. It maintains normal heart rate and minimizes peripheral vasoconstriction which allows for more accurate NIBP measurements. Aside from optimizing MRI anesthesia, a normothermic patient will have a better surgical outcome, including minimizing coagulopathies and infection.

Finally, a normothermic patient will recover more quickly and smoothly than a hypothermic pet. Luckily, Hallmarq’s small animal 1.5T MRI includes a self-shielded RF hatch so has the benefit of maintaining temperature more reliably than other systems. Recommendations for maintaining temperature include a heated table at induction during prep for MRI, blankets for maintaining temperature in the MRI, and the use of ConRad thermal blankets, which have been remarkably reliable in maintaining temperature.

How to Deal With an Anesthetic Emergency During MRI

• This tacklebox should not be used outside of emergencies and should be checked for expiration regularly and instrumented with a lock to ensure it is well stocked at all times
• The location of the defibrillator should be known and should be accessible to bring to the MRI area
• Extra endotracheal tubes, an MRI compatible laryngoscope, reversal drugs, and CPR drugs should be included (see Fig 1. below for drugs available)

Post-Anesthetic Complications

All patients should have TPRs monitored until extubated, normothermic, and QAR, and allowed to recover in sternal recumbency to improve oxygenation and prevent aspiration. Complications may include:

• Hypothermia: will cause delayed recovery and patients may require drug reversal. Ensure active warming is provided

• Pain: full-mu, partial Mu agonist, NSAID, or NMDA antagonist can be provided. Consider local blocks if possible, during surgery

• Dysphoric recovery: consider pain as differential. Consider reversing opioids if the surgery is non-painful or planned. Butorphanol or Naloxone are options for pure mu opioids; Naloxone will reverse Butorphanol. Sedation may be needed: Acepromazine 0.005-0.01 mg/kg IV or Dexmedetomidine 0.5-1 ug/kg IV

• Delayed recovery: check rectal temperature to ensure the patient is not hypothermic. If ICP is increased, consider hypertonic saline or mannitol. Consider reversal if non-painful or no surgery planned

Key Takeaways for Small Animal Neurology Specialists

With proper preparation, MRI anesthesia can be safe, efficient, and stress-free. Using MRI-compatible monitoring systems, maintaining normothermia, and clear team communication ensures better outcomes for small animal neurology patients.